Ois Podcast

Scientist, entrepreneur, and executive Thomas Chalberg, PhD, has developed or funded companies that have advanced complex gene therapy technology, a novel anesthesia delivery system, and a lens that helps slow myopia progression in kids. And that’s just the start.A leader in gene therapy development who is recognized by the World Economic Forum as a Technology Pioneer, Dr. Chalberg cofounded Avalanche Biotechnologies, which is now Adverum Biotechnologies. There, he built the Avalanche Ocular BioFactory, an adeno-associated virus (AAV)–based, proprietary, next-generation platform for the discovery and development of gene therapy vectors for ophthalmology.While much of his career has centered on gene therapy, one of his more recent ventures, SightGlass Vision, falls on the opposite end of the spectrum. The company has developed a novel spectacle lens design that helps slow myopia progression. Its foundation stems from research by the University of Washington, which found that high retinal contrast signaling lea