American Journal Of Psychiatry Audio

This audio program discusses take-home messages from the Treatment for Adolescents with Depression Study; change in negative affective bias in depressed patients after one subtherapeutic dose of an antidepressant; association between the familial aggregation of suicide and cluster B personality traits; associations among suicide attempts, gender, and sexual abuse; and a national survey of at-risk and binge drinking among middle-aged and elderly adults. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the treatment of depression in preschool children; the relationship between sudden death and use of stimulant medications in youths; long-term benefits from a short-term quality improvement intervention for depressed youth in primary care; identifying genes that may be relevant to major depression via an overlap between two species in altered gene expression in the anterior cingulate cortex and amygdala; the interaction between family history and prenatal exposure to infection in the causation of schizophrenia; association of substance use disorders with childhood trauma, but not with African genetic heritage, in an African American cohort. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses a successful repeat trial of ECT 2 months after an earlier ECT series induced left ventricle cardiomyopathy; manualized short-term psychodynamic psychotherapy versus CBT in the treatment of generalized anxiety disorder; a long-term study differentiating youths with persistent conduct problems from those whose disorder is limited to childhood; an intervention for reducing suicidal ideation and depression in older primary care patients; the relationship between autistic traits in neurotypical adults and functional connectivity in a brain region commonly implicated in social cognition. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses compulsive checking as part of PTSD in veterans of the Iraq and Afghanistan wars; a new foster care network in Bucharest, Romania; the effects of bereavement 21 months after the sudden death of a parent; the 4-year course of bipolar disorder in children and adolescents; an auditory training program designed to improve verbal memory in patients with schizophrenia; and a postmortem analysis differentiating the expression of type 2 and type 3 metabotropic glutamate receptors in the brain to clarify an agonist’s antipsychotic action. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses cognitive complaints and depression following mild traumatic brain injury; cognitive effects of antipsychotic drugs in first-episode patients; the relationship between prenatal infection and executive dysfunction in adults with schizophrenia; activity in the basal ganglia of depressed patients during the anticipatory and consummatory phases of reward processing; whether inhibitory control can be used as a trait marker of ADHD; and a comparison of extended-release paliperidone with quetiapine and placebo for schizophrenia patients requiring hospitalization. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses dynamic psychotherapy for borderline personality disorder; how both major depression and antidepressant treatment affect pregnancy and neonatal outcomes; delusions in the general population; the effect of second-generation antipsychotics on patients with Alzheimer’s disease; and the risk of diabetes mellitus after long-term use of antidepressants. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses treatment of postpartum psychosis; predictors of suicidal events among depressed adolescents receiving antidepressant treatment after an unsuccessful trial of an SSRI; whether clinicians can recognize DSM-IV personality disorders from case descriptions based on the Five-Factor Model of personality; a genome-wide scan of families with Mexican or Central American ancestry that identified two new loci likely to harbor genes that carry a predisposition for schizophrenia and schizoaffective disorder; the isolation of a risk allele associated with schizophrenia; and the relationship between neural habituation in the amygdala and social impairments in autism spectrum disorders. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses the psychiatric evaluation and follow-up of patients receiving bariatric surgery; a clinical trial of CBT for patients with a variety of eating disorder diagnoses; a study that measured anticipatory activation in the amygdala and anterior cingulate of untreated patients with generalized anxiety disorder with posttreatment examination of the relationship of this activation to treatment response; a study on obsessions and compulsions in the general population from following members of a birth cohort until age 32; the connections between the use of SSRI antidepressants during pregnancy and the risk of gestational hypertension; the ramifications of giving placebo to depressed adolescents in clinical trials. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses factors related to the emergence of mania during antidepressant treatment for bipolar depression; manic symptoms observed during bipolar depression among STEP-BD participants; the attitude of older adults toward enrollment of noncompetent subjects in Alzheimer’s disease research; the association between cerebral deficits and clinical symptoms in antipsychotic-naive, first-episode schizophrenia patients; whether altered amygdala activity in schizophrenia is related to clinical state or to genetic risk; brain structure in schizophrenia patients with relatively intact cognitive functioning; and an odor-detection sensitivity deficit in patients with schizophrenia and its implications for cyclic AMP signaling. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program discusses treatment of children for whom the differential diagnosis includes bipolar disorder and attention deficit hyperactivity disorder; placebo response in antidepressant trials for children; a longitudinal study comparing cortical thickness in patients with ADHD who took stimulants, patients who didn’t take stimulants, and normally developing youths; an examination of the volume and shape of the basal ganglia in ADHD conducted with large-deformation diffeomorphic metric mapping; a study of disorder-specific brain dysfunction in boys with ADHD only and boys with conduct disorder only; and a report on repeat incarcerations for prisoners with serious mental illness. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program includes a Treatment in Psychiatry feature that focuses on prison inmates with ADHD; the association between sleep disturbance and the recurrence of depression among older adults; melatonin circadian rhythms in pregnancy and the postpartum period among depressed women and those with a personal or family history of depression; effect of interpersonal and social rhythm therapy on occupational functioning for patients with bipolar disorder; trauma, resilience, and recovery in a high-risk African American population; association between reading skills in the general population and a gene for dyslexia; and deficits in GABA markers in schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program features the role of culture in psychodynamic psychotherapy; two clinical trials of antipsychotic medications for children and adolescents; a clinical trial of naltrexone in the treatment of amphetamine dependence; a diagnostic study that identified differences and similarities between depression following bereavement and depression associated with other stressful life events; and an analysis indicating that cognitive function in older adults is influenced by the interaction between cortisol and the genotype for apolipoprotein E. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program features a discussion of drug treatment of breast cancer and depression; highlights a study in which olanzapine was used to treat low body weight and obsessive thinking in women with anorexia nervosa; examines whether compulsive hoarding is a symptom of OCD, a distinct syndrome, or both; discusses a clinical trial of adjunctive aripiprazole for bipolar mania patients partially nonresponsive to valproate or lithium monotherapy; and compares two sets of criteria for diagnosing PTSD in children exposed to motor vehicle accidents. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program highlights the treatment of body dysmorphic disorder, three articles on the effect of parental mood disorders--and their treatment--on child psychopathology outcomes, risk for nicotine dependence, remission from alcohol dependence, and a genome screen for quantitative trait loci influencing schizophrenia and neurocognitive phenotypes. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents the diagnosis and treatment of Asberger’s syndrome, new treatments for schizophrenia, the pharmacokinetics of aripiprazole, the relationship of cognition and psychopathology to functional impairment in schizophrenia, brain anatomy comparisons of first-episode and chronic schizophrenia, and new evidence of frontal lobe dysfunction in schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents a case discussing the resumption of clozapine treatment after development of neutropenia, antipsychotic treatment of Alzheimer’s disease symptoms, a treatment decision tree for depression in elderly patients, and a possible physiologic marker of panic disorder. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program presents a clinical case conference describing the use of deep brain stimulation after a cingulotomy had provided only short-term benefit; highlights a report on the economic impact of mental disorders in the United States; features an imaging study of the amygdala in adolescents with disruptive behavior disorders who also exhibit callous and unemotional traits; presents a direct comparison of atomoxetine and methylphenidate for treating attention deficit hyperactivity disorder; and describes a large study linking greater memory impairment to a longer history of past depression. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program summarizes a clinical case illustrating the interactions between depression and comorbid chronic illnesses as well as new research on the cost-effectiveness of treatments for adolescent depression, the relationship between childhood treatment for ADHD and later substance abuse, long-term treatment of patients with borderline personality disorder, and the effect of race in facial processing by African American and Caucasian individuals with schizophrenia. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program summarizes how to teach supportive psychotherapy; continuation treatment with fluoxetine in treatment-responsive children and adolescents; a group treatment program for borderline personality disorder; regional expression of GABA-related genetic transcripts in the neocortex of schizophrenia patients; the relationship between cannabis use and loss of brain volume in schizophrenia; and the association of nicotine dependence with low dopamine D2 receptor availability in the striatum. Articles can be viewed online at www.ajp.psychiatryonline.org.

This audio program summarizes research on depressed adolescents at high risk of suicidal behavior; adding D-cycloserine to behavior therapy for obsessive-compulsive disorder; treatment outcome for patients with anxious depression; the addition of the diabetes drug metformin to olanzapine to prevent weight gain in first-episode patients; the course of rapid-cycling bipolar disorder; and the effect of methadone on brain responses to drug-related cues. Articles can be viewed online at www.ajp.psychiatryonline.org.