Let's Know Things

This week we talk about OxyContin, opium, and the British East India Company.We also discuss isotonitazene, fentanyl, and Perdue.Recommended Book: The Thinking Machine by Stephen WittTranscriptOpioids have been used as painkillers by humans since at least the Neolithic period; there’s evidence that people living in the Iberian and Italian Peninsulas kept opium poppy seeds with them, and there’s even more evidence that the Ancient Greeks were big fans of opium, using it to treat pain and as a sleep aid.Opium was the only available opioid for most of human history, and it was almost always considered to be a net-positive, despite its downsides. It was incorporated into a mixture called laudanum, which was a blend of opium and alcohol, in the 17th century, and that helped it spread globally as Europeans spread globally, though it was also in use locally, elsewhere, especially in regions where the opium poppy grew naturally.In India, for instance, opium was grown and often used for its painkilling properties, but