Oncology Times - Ot Broadcasts From The Ipad Archives

This episode is Research Review, a quarterly review of the research you may have missed. Today, we are covering the American Society of Hematology Annual Meeting highlights. First Up, results from the ECOG-ACRIN E1910 Randomized Phase III clinical trial showed that blinatumomab improved overall survival in newly diagnosed adult patients with b-lineage acute lymphoblastic leukemia. First author of this new research, Mark Litzow, MD, from the Mayo Clinic in Rochester, MN, talked with journalist Peter Goodwin at the ASH Annual Meeting. They discussed the use of blinatumomab in patients whose initial therapy for acute lymphoblastic leukemia had achieved minimum residual disease—MRD (Abstract LBA-1). Next, researchers explored the potential of using genomic DNA and RNA profiles in a machine-learning algorithm to predict which patients with acute myeloid leukemia or advanced myelodysplastic syndrome will respond to venetoclax-based therapy (Abstract 2789). Maher Albitar, MD, discussed the findings. Moving on, the d