Corconsult Rx: Evidence-based Medicine And Pharmacy

On this episode, we review several drugs that have been approved by the FDA over the last year. The list of drugs that we review are below: Brexafemme (ibrexafungerp) Wegovy (semaglutide) Aducanumab (Aduhelm) Kerendia (finerenone) Zimhi (naloxone hydrochloride) Tyrvaya (varenicline) Nasal Spray PreHevbrio (hepatitis B vaccine (recombinant) Verquvo (vericiguat) Cabenuva (cabotegravir and rilpivirine) Extended-Release Injectable Evkeeza (evinacumab-dgnb) Injection Azstarys (dexmethylphenidate and serdexmethylphenidate) Lybalvi (olanzapine and samidorphan)  Tezspire (tezepelumab-ekko) Injection Leqvio (inclisiran) Injection Quviviq (daridorexant) Ruxolitinib (Opzelura) cream Tralokinumab (Adbry) Abrocitinib (Cibinqo) Cole and I are happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast episode! We continue to partner with freeCE to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. To earn credit for

On this episode, we discuss dry eye disease (also known as keratoconjunctivitis sicca). We give some basic background information including pathophysiology and signs/symptoms. We then compare and contrast the various artificial tear products based on the information from "Artificial tears potpourri: a literature review" (PubMed ID below). We then discuss the roles of ophth cyclosporine, ophth lifitegrast, and nasal varenicline. PMID: 25114502 Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based m

On this episode, we review the treatment of dermatophyte (tinea) infections.  Hey guys, we’re happy to share that our listeners can claim ACPE-accredited continuing education for listening to this podcast! We continue to partner with freeCE to provide listeners with the opportunity to claim 1-hour of continuing education credit for select episodes. To earn credit for this episode, visit the link provided in the show description to earn CE for listening to this podcast episode: https://hubs.ly/Q015P7cg0 For existing freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. Use the password RINGWORM (all caps) to unlock the post-test for this episode.   But if you’re not currently a freeCE member, we definitely suggest you explore all the benefits of their Unlimited Membership on their website and earn CE for listening to this podcast. CorConsult Rx listeners can save 15% off the

On this episode, we review the management of Crohn's Disease. We go over the newest guidelines and some of the supporting clinical data. We end by discussing the U.S. Preventive Services Task Force's colorectal cancer screening recommendations.  Once again, we’re excited to announce that our listeners can claim ACPE-accredited continuing education for listening to our podcasts! We’re partnering with freeCE by PharmCon, to provide listeners with the opportunity to claim 1-hour of continuing education credit each month. To earn credit for this episode, visit the following link for more information about earning CE for listening to our podcasts: https://hubs.ly/Q012N29c0 For freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. Use the password COLON (all caps) to unlock the post-test for this episode. If you are not currently a freeCE member, we invite you to explore all the b

On this episode, we review the data for tirzepatide, a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 (GLP-1) receptor agonist that is under development for the treatment of type 2 diabetes a new medication that is being investigated. We discuss the unique mechanism of action and summarize the data from the SURPASS studies.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for education

On this episode, we review medication regimens for special patient populations. We start with a quick overview of CYP450 drug-drug interactions. We then discuss safety conerns when starting medications in a patient that is pregnant, is at an increase risk for a bleed, renal impairment, and hepatic impairment. Once again, we’re excited to announce that our listeners can claim ACPE-accredited continuing education for listening to our podcasts! We’re partnering with freeCE by PharmCon, to provide listeners with the opportunity to claim 1-hour of continuing education credit each month. To earn credit for this episode, visit the following link for more information about earning CE for listening to our podcasts: https://hubs.ly/Q012N29c0 For freeCE members, this CE option is included in your membership benefits at no additional cost! Members can simply follow the link above to take the post-test and evaluation for this activity. Use the password SAFETY (all caps) to unlock the post-test for this episode. If you are

On this episode, we discuss some of the basics of treating a patient with hepatitis C. We list the labs that should be drawn prior to starting treatment as well as non-invasive ways of assessing fibrosis/cirrhosis. We also review some information about the pangenotypic medications, Epclusa and Mavyret.  Click the following link to see the upcoming events from the Southeast Viral Hepatitis Interactive Case Confirmation (SVICC):  https://www.seaetc.com/ Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current eviden

On this episode, Cole and I are joined by Trevor Walker, PharmD Candidate 2022. We begin by comparing and contrasting the original SSRIs as well as new agents like vortioxetine and vilazodone. We then review some serotonin (5-HT) receptors and how their activity (or inhibition) determine and mitigate outcomes and adverse effects. We close by reviewing the ANTLER trial that was published in NEJM in September 2021.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatme

On this episode, we discuss the management of endometriosis. We begin with some background information including risk factors, sign and symptoms, and more. Then we review the common first-line agents used, sometimes even before a definitive diagnosis via laparoscopy. We then compare and contrast more specialized treatment options including gonadotropin-releasing hormone agonists with add-back therapy, gonadotropin-releasing hormone antagonists, and androgen therapy.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast review

On this episode, we review the 2021 Focused Update Guidelines on Management of Clostridioides difficile Infection in Adults published by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA).  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients a

On this episode, we are joined by the host of the Pharm So Hard podcast, Dr. Jimmy Pruitt, PharmD, BCPS, BCCCP, to discuss the 2021 Surviving Sepsis Campaign Guidelines. The guidelines can be found at the Society of Critical Care Medicine's website: SCCM Sepsis Guidelines For more critical care educational content, make sure you check out Dr. Pruitt's new website: Acute Care University Follow the Pharm So Hard Instagram page: Pharm So Hard IG Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable PowerPoint slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based

On this episode, we discuss the prevention and acute management of migraines. We start by reviewing the pathophysiology associated with a migraine. We then compare and contrast various pharmacological classes utilized in migraine prophylaxis as well as acute relief of symptoms.  Once again, we are excited to announce that listeners can claim ACPE-accredited continuing education for this episode! We have partnered with freeCE, which allows our listeners to claim 1 hour of continuing education credit by visiting the following link https://hubs.ly/H0_kw9p0 For freeCE members, this service is included in your membership benefits at no additional cost! Simply follow the link above to take the post-test and evaluation for this activity. Use the password RELIEF (all caps) to unlock the post-test for this episode. If you are not currently a freeCE member, we invite you to explore all the benefits of their unlimited membership on their platform. freeCE offers hundreds of live webinars, on-demand webcasts, home study m

On this episode, we are joined by Dr. Spencer Carter, MD and Dr. Kyle Fischer, PharmD, to discuss preserved ejection fraction heart failure. Dr. Carter is a cardiologist finishing his fellowship that is focused on heart failure and cardiac transplant.  Dr. Fischer is currently a PGY1 general clinical pharmacy resident. We begin by discussing some background information including pathophysiology and the clinical differences of HFpEF compared to HFrEF. We then review the medications often utilized in HFpEF. We finish with a deep dive into the new data surrounding sacubitril/valsartan in chronic heart failure (PARAGON HF) and the SGLT-2 inhibitors (EMPEROR-Preserved, DELIVER).  Follow Dr. Carter on Twitter: @spencercarter55 Follow Dr. Fischer on Twitter and Instagram: @Kfischer_10 and @kgfischerx Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each

On this episode, we review the pharmacotherapy options for managing Parkinson's disease. We begin with some background pathophysiology/etiology. Then, we compare and contrast the various medication options available.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or

On this episode we are joined by MUSC P4, Calynn Dioses, to discuss medications that help patients with their weight loss goals.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patients and not intended as advice or treatment.

On this episode, we discuss the use of hormone therapy in perimenopausal/menopausal women. We give some background information as well as labs that should be monitored. We then separate the therapy options based on whether the patient is experiencing vasomotor symptoms, vulvovaginal symptoms, or a combination of both. We close by reviewing the results of the Women’s Health Initiative (WHI) study.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This

On this episode, we discuss the management of rheumatoid arthritis. We start by reviewing some background information. Then, we compare and contrast the various medications options including DMARDs, TNF-alpha biologics, and non-TNF-alpha biologics.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for patien

On this episode, we are joined by 4th year, MUSC students, Shannon Himes and Blake Adams. We discuss a patient case that involves HFpEF (with uncontrolled hypertension), type-2 diabetes, stage 2 chronic kidney disease, and benign prostatic hyperplasia.  Thanks for listening! If you want to support the podcast, check out our Patreon account. Subscribers will have access to all previous and new pharmacotherapy lectures as well as downloadable Power Point slides for each lecture. You can find our account at the website below:  www.patreon.com/corconsultrx If you have any questions for Cole or me, reach out to us on any of the following: Text - 415-943-6116 Mike - mcorvino@corconsultrx.com Cole - cswanson@corconsultrx.com Instagram and other social media platforms - @corconsultrx This podcast reviews current evidence-based medicine and pharmacy treatment options. This podcast is intended to be used for educational purposes only and is intended for healthcare professionals and students. This podcast is not for pa